A long noncoding RNA promotes cellulase expression in Trichoderma reesei

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A long noncoding RNA promotes cellulase expression in Trichoderma reesei

Background Due to its capability to secrete large quantities of plant biomass degrading enzymes (PBDE), Trichoderma reesei is widely applied for industrial purposes. In nature, expression of PBDE is efficiently regulated in this fungus. Several factors involved in this regulatory network have been identified. However, most of them are transcription factors. Long noncoding RNAs (lncRNAs) emerged...

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Fingerprinting Trichoderma reesei hydrolases in a commercial cellulase preparation.

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Cellulase production by the fungus Trichoderma reesei was studied using sugar beet pulp (SBP) as a substrate. The subculture medium was a salt solution consisting of KH2PO4, CaCl2, etc. Fungal cells were sub-cultured in an orbital shaker (180 rpm) at 30°C for 1-2 generations (two days for each generation) and were then used as an inoculum. Exponential cells were inoculated into a medium contain...

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Construction of a cellulase hyper-expression system in Trichoderma reesei by promoter and enzyme engineering

BACKGROUND Trichoderma reesei is the preferred organism for producing industrial cellulases. However, a more efficient heterologous expression system for enzymes from different organism is needed to further improve its cellulase mixture. The strong cbh1 promoter of T. reesei is frequently used in heterologous expression, however, the carbon catabolite repressor CREI may reduce its strength by b...

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ژورنال

عنوان ژورنال: Biotechnology for Biofuels

سال: 2018

ISSN: 1754-6834

DOI: 10.1186/s13068-018-1081-4